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Caution should be taken with any patient with GI problems, coronary disease, respiratory dysfunction, renal or hepatic disease, alcoholism, or hyperthyroidism because these conditions can be exacerbated by the systemic effects of xanthines

2020 Tobacco-free pharmacies: State action: In April 2020, New York became the second state to prohibit the sale of tobacco products at pharmacies Federal action on flavored tobacco products: On January 2, 2020, the FDA issued final guidance prohibiting the sale of flavored cartridge-based (closed system) e-cigarette products other than menthol or tobacco flavor

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More than 400ml/day is not adequate for screening purposes