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Clinical significance is unknown, but caution is reasonable
Hydroxyethyl starch inhibits glycocalyx-degrading enzymes, facilitating the restoration of glycocalyx thickness and enhancing expression of VE-cadherin, occludin, and zonula occludens-1, reducing albuminfluorescein isothiocyanate infiltration, and improving pulmonary vascular permeability [45]
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Your provider will assess your current protocol and determine whether adding peptide therapy makes sense for your goals
TJs, composed of claudins, occludin, junctional adhesion molecules (JAMs), and the zonula occludin (ZO) family, are believed to regulate vascular paracellular transport by forming a high-resistance electrical barrier [17]
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