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These can include: a weakened immune system because of illness or stress hormone changes, such as menstruation a vitamin deficiency, especially of folate and B12 intestinal issues, such as Crohns disease or ulcerative colitis, both types of inflammatory bowel syndrome (IBS) exposure to toxins in drinking water emotional or psychological stress smoking or a history of smoking Cold sores Cold sores look like fluid-filled blisters that appear near the mouth and lips

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Awareness and use of e-cigarettes among Filipino adults: evidence from the 2015 and 2021 Global Adult Tobacco Surveys Rutcher Madera Lacaza, Edrei Yambao Udaundo BMJ Public Health 25

The study concluded that a multi-personal approach necessitating teachers and parents effectively slashes smoking prevalence among adolescents as proposed in a study by Carrin-Valero et al

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