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Additionally, cannabis is not always the only drug or substance that someone might be using

We are just trying to make sure that we provide the safest care. In Colorado, Hawkins said, anesthesiologists have noticed that patients who use marijuana are more tolerant of some common anesthesia drugs, such as propofol, which helps people fall asleep during general anesthesia or stay relaxed during conscious twilight sedation

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Moreover, nicotine also exerts aversive properties, particularly though the medial habenula to interpeduncular nucleus pathway (95)