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Study 7 was a 64-week trial that enrolled 307 patients with obesity (BMI greater than or equal to 30 kg/m2) or with overweight (BMI 27-29.9 kg/m2) and at least one weight-related comorbid condition, such as treated or untreated dyslipidemia or hypertension

JAMA (2023)

Some patients feel energized and positive about starting treatment, while others experience mild fatigue or gastrointestinal discomfort that temporarily affects their quality of life

Hormonal changes during rapid weight loss affect melatonin and cortisol rhythms

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