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The association did not replicate in UK Biobank, although the expected power for replication in this cohort was low (Supplementary Table 11 and Supplementary Information)

In summary, despite the lack of formal long-term safety data on epithalon, we do not note any safety issues associated with the peptide

Serotonin involvement in Rhodiola rosea attenuation of nicotine withdrawal signs in rats

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doi:10.1038/nature09922 13

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