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This delayed gastric emptying is what creates the sensation of fullness and reduces appetite

10.1038/nm.4517 Nat

Makker K, Agarwal A, Sharma R

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For oral semaglutide 3 mg, 7 mg and 14 mg vs sitagliptin 100 mg, the estimated treatment differences (ETDs [95% CI]) were 2 (4, 1) mmol/mol, 8 (9, 6) mmol/mol and 11 (12, 9) mmol/mol, respectively

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