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Three groups were identified: participants with current MDD (that is, participants meeting DSM-IV criteria for MDD within the past 6 months), with remitted (i.e., lifetime but not current) MDD, and healthy controls (without any lifetime depressive/anxiety disorder)

with FDA-approved products containing semaglutide (Ozempic, Wegovy, and Rybelsus, for which it claims to hold various trademarks and patents)

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Weight loss during week one is typically 0-2 pounds

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As Healio previously reported from the primary analysis of SURMOUNT-5, adults with overweight or obesity who received tirzepatide (Zepbound, Eli Lilly) reached a weight reduction of 20.2% at 72 weeks compared with a 13.7% weight loss for adults receiving semaglutide (Wegovy, Novo Nordisk), according to the treatment-regimen estimand