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Hormonal deficiencies and mineral imbalances are common as well

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Most formulations remain stable at room temperature (5986F) for up to 28 days, though refrigeration between 3646F extends shelf life significantly

Proc Natl Acad Sci 107(30):1343213437 Kim WK, Meliton V, Tetradis S, Weinmaster G, Hahn TJ, Carlson M, Nelson SF, Parhami F (2010) Osteogenic oxysterol, 20 (S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells