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Nicotine use is the leading cause of preventable deaths in the United States Nicotine use can result in short-term feelings of pleasure, reduced stress, increased focus, and suppressed appetite

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These are considered pre-cancerous

Jasjit Ahluwalia, an addiction specialist at Brown University

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Single and multiple-dose pharmacokinetics of varenicline have been investigated in pediatric patients aged 12 to 17 years old (inclusive) and were approximately dose-proportional over the 0.5 mg to 2 mg daily dose range studied