PGC-1 is a pivotal regulator of mitochondrial biogenesis and mitophagy (Palikaras and Tavernarakis, 2014)
Alpha-melanocyte-stimulating hormone (-MSH) is part of a larger molecule called POMC that also gives rise to endorphins
That means starting with a low dose and gradually increasing it over several weeks
5-Amino-1MQ Vials (50 mg each): 1 week (5 mg/day) 1 vial 2 weeks (5 mg/day) 1 vial 4 weeks (5 mg/day) 2 vials Insulin Syringes (U-100): Per week (once daily): 7 syringes Per week (BID): 14 syringes 4 weeks (once daily): 28 syringes Bacteriostatic Water (10 mL bottles): Use 4.0 mL per vial for reconstitution
However, the COVID-19 pandemic shifted this dynamic
Other reported side effects were mostly local to the injection site, including pain, the formation of nodules, swelling, redness, itching, a warm sensation, and discoloration