These factors may not constitute all factors that could cause actual results to differ from those discussed in any forward-looking statement
139,140 Alkyl-adenine DNA glycosylase (AAG) is a critical enzyme that removes methylated DNA bases in BER
doi: 10.7759/cureus.25946, 12
Patients who underwent metabolic surgery showed significantly increased genus richness (ie, diversity) in the gut microbiota compared with those on standard medical therapy, which was correlated with an improvement in metabolic and inflammatory biomarkers (Lau 2021)
Since many enzymes that mediate inflammatory and anti-inflammatory processes require the same cofactors to function, this raises the possibility that under conditions where the abundance of these cofactors is limited, inflammatory and anti-inflammatory enzymes must compete with each other for the consumption of cofactors
These metabolic shifts often persist even if a patient temporarily pauses the medication, suggesting durable physiological change rather than temporary fluid loss or muscle depletion
