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This increase in excitability may result from neuroexcitatory effects caused by disrupted balance between inhibitory (-aminobutyric acid-mediated) and excitatory (cholinergic) signalling, indicating possible neuronal hyperactivation [157]

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If using the nasal spray, follow the pharmacys priming and administration instructions carefully, and dont sniff too hard (you want it to stay in the nasal mucosa, not drip down the throat)