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When the lower esophageal sphincter weakens, stomach contents may reflux into the esophagus, causing heartburn and possibly damaging the lining of the esophagus

Adequate levels of testosterone are important for preventing conditions like osteoporosis

10.1038/nrcardio.2017.36 Nat

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Dagdelen S, Eren N, Karabulut H, Akdemir I, Ergelen M, Saglam M, Yce M, Alhan C, Caglar N: Estimation of left ventricular end-diastolic pressure by color M-mode Doppler echocardiography and Tissue Doppler imaging