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BP, a commonly used apitherapeutic, varies in chemical composition depending on geographic origin, plant source, soil type, bee race, activities, and climatic conditions (8, 11, 30, 46, 81)

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They are unable to aggregate while in their natural water-soluble state and must first undergo modifications to decrease solubility and generate a build-up of proteins (Moreau & King, 2012)

[DOI] [PubMed] [Google Scholar] 83.Andersen O, Nielsen JB