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Signal Transduction and Targeted Therapy, 8 , 345

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It functions as a triple receptor agonist at the GIP, GLP-1, and glucagon receptors

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Contraindications include uncontrolled hypertension, coronary artery disease, and hyperthyroidism

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In Phase 2 trials, participants with type 2 diabetes achieved A1C reductions averaging 2.02%

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