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The study analyze shows that intracellular administration of LfcinB(2025) via fusogenic liposomes results in powerful cytotoxic activity involving the action of caspases and cathepsin B without requiring ROS generation [45].The mechanism underlying this peptide emphasizes that it could be used as a novel drug delivery system, maximizing its efficacy [46]

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Pharmacological chaperone approaches for rescuing GPCR mutants: current state, challenges, and screening strategies

Through cysteine provision, NAC facilitates de novo GSH synthesis by gamma-glutamylcysteine synthetase (GCS), the GSH-producing rate-limiting enzyme, thereby restoring cellular levels of GSH