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397 Bispecific antibodies are also promising strategies for p53 mutation-related tumor immunotherapy

doi: 10.1093/bja/aer058

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Clinically, it is considered among the least concerning for long-term use

During the 52-week treatment period and 4-week follow-up, the incidence rates of treatment-emergent adverse events (TEAEs) in adult patients receiving 100 mg Resmetirom (325 patients), 80 mg Resmetirom (327 patients), placebo (320 patients), and 100 mg Resmetirom in an open-label trial (171 patients) were 86.1%, 88.4%, 81.8%, and 86.5%, respectively

Pyridoxine appears to improve the behavioral side effects (discussed below)