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Dietary allicin reduces transformation of L-carnitine to TMAO through impact on gut microbiota

10.1007/s12325-008-0136-5

doi:10.1111/j.1467-789X.2007.00413.x Smith, R

This process in turn involves more extensive damage to the liver

GPX4-independent antioxidative pathways While the system x c GSHGPX4 axis is acknowledged as the main antilipid peroxidation pathway in ferroptosis, recent studies have identified three GPX4-independent mechanisms that also inhibit ferroptosis: ferroptosis suppressor protein 1 (FSP1)/CoQ10, GTP cyclohydrolase 1 (GCH1)/tetrahydrobiopterin (BH4), and dihydroorotate dehydrogenase (DHODH)