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Among the various mechanisms involved in ferroptosis, ferritinophagy is a selective type of autophagy that specifically targets intracellular ferritin for degradation, facilitating iron recycling in cellular processes (363, 364)

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However, it is very hard to delineate the precise effect of nutrients or bioactive food components on each epigenetic modulation and their associations with physiologic and pathologic processes in our body, because the nutrients also interact with genes, other nutrients, and other lifestyle factors

It is a quaternary ammonium compound that the body synthesizes from the amino acids lysine and methionine, primarily in the liver, kidneys, and brain