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By binding GLP-1 receptors, it slows gastric emptying, reduces appetite and improves insulin sensitivity
[DOI] [PMC free article] [PubMed] [Google Scholar] 158.Hanson L.R., Frey W.H., II Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease
While preliminary studies and observational signals suggest potential thyroidal effects, no RCTs have evaluated progression of Hashimoto thyroiditis or Graves disease under GLP-1RA therapy [32,58]
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Individuals with a BMI of 25 or higher
Another effect of GLP-1RA is the increase of sympathetic nervous system (SNS) activity
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