Ozempic for diabetes received approval specifically for managing type 2 diabetes, while Wegovy for weight loss earned approval solely for chronic weight management
The resolution of this apparent paradox is that glucagon receptor activation also drives energy expenditure through two well-documented mechanisms: Thermogenesis: GCGR activation in brown adipose tissue (BAT) and, to a lesser extent, skeletal muscle increases uncoupled heat production, raising resting energy expenditure
Which therapy causes the greatest weight loss
In theory, this could potentially lead to a higher risk of hypoglycemia when taking an antidepressant while on Ozempic (since Ozempic definitely lowers blood sugar)
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