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Glucose and Hemoglobin A1c (HbA1c): Semaglutide's primary mechanism involves enhancing glucose-dependent insulin secretion and suppressing glucagon release

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Mechanistically, the metabolic benefits of Godex depend on enhanced activity of CrAT, which modulates mitochondrial acetyl-CoA metabolism and thereby improves insulin sensitivity and hepatic lipid homeostasis (33)

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Another retrospective study (2023) focusing on dulaglutide in T2D reported lower incidence of new-onset moderate-to-severe ED in the group on dulaglutide over 12 years compared to those not on it

Weight management : Modest weight loss (5-10% of body weight) in individuals with overweight or obesity can improve metabolic parameters and potentially enhance endogenous GLP-1 activity