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ADVERSE EFFECTS Some epidemiologic evidence indicates that long-term use of acetaminophen is associated with an increased risk of renal dysfunction .M Although therapeutic doses of acetaminophen are remarkably nontoxic, the ingestion of 20 to 30 tablets is sufficient to cause life-threatening hepatotoxicity .

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This effect was reversed when melatonin-deficient animals were supplemented with melatonin [114]

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This is particularly beneficial for individuals recovering from illness or dehydration caused by intense physical activity

A pilot study of the effect of inhaled buffered reduced glutathione on the clinical status of patients with cystic fibrosis