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Furthermore, a meta-analysis including 38 studies with schizophrenia cases and controls showed the association between C677T polymorphism and risk of schizophrenia in all three ethnic populationsAfrican, Asian, and Caucasian 54

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Conversely, inhibiting TLR4 can suppress microglial activation, alleviate neuroinflammation, improve cognitive function, and mitigate synaptic plasticity impairments and depression-like symptoms via this pathway (159, 160)

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J., Yagi, T., & Felding-Habermann, B

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