This increase was accompanied by a decrease in the -2 and -4 subclusters
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Cigarette smoking-associated alterations in serotonin/adrenalin signaling pathways of platelets
This biochemical process is also involved in the protection against environmental toxicants, carcinogens, dietary toxins and participates in the homeostasis of numerous endogenous molecules, including bilirubin, steroid hormones and biliary acids
Consistently, Reactome (REAC) analysis revealed that CHL-upregulated proteins were significantly enriched in the innate immune system ( p adjusted = 3.1E-12), complement cascade ( p adjusted = 6.6E-07) and antimicrobial peptides ( p adjusted = 3.5E-08)
