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FIGURE 2 6 Impact of anesthetic agents on gut microecology 6.1 Inhalational anesthetics Animal studies suggest that sevoflurane exposure can rapidly reduce gut microbial -diversity, with depletion of Firmicutes and Clostridiales and a concurrent expansion of Proteobacteria ( Beyond direct effects on microbial composition, inhalational agents may also induce cytotoxic effects on intestinal epithelial cells

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