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thus, further research into the effects of therapeutic intervention targeting ApoC-III on atherosclerotic coronary plaques and ASCVD events is anticipated

This is the big one, right

The STEP 8 trial provided a definitive head-to-head comparison, establishing semaglutide's clear superiority

With retatrutide dosing , the same principle applies

Gilbert, Rosenthal, March 2024)

Only your clinician can determine if semaglutide is the cause and whether to change the dose or stop the drug, and they may recommend temporarily holding the medication, slowing the dose increase, or switching treatments if needed