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Days to weeks to replenish the depleted vesicular monoamine transporters (VMATs), monoamine oxidase (MAO), as well as catechol-O-methyltransferase (COMT), metabolize unprotected neurotransmitters, given the post-synaptic cell are consequently never excited [154,155]

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There were 61 patients with RET -altered MTC who had previously received cabozantinib, vandetanib, or both, and 23 patients were treatment-nave

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Simulating the effects of in vitro drug treatment, phenylephrine (PE) stimulation was given for 48 hours, and drug treatment was given for 48 hours