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Common side effects include nausea, vomiting, constipation, and abdominal discomforttypically mild and transient with slow dose titration

Their studies in swine and rat models demonstrated that ipamorelin stimulated GH release in a dose-dependent manner comparable to GHRP-6, but without the corresponding increases in ACTH or cortisol that accompanied GHRP-6 administration

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Total protein was extracted from BV2 cells and hippocampal tissues using a Whole Protein Extraction kit, and the protein concentrations were determined using a BCA Protein Assay kit (both Nanjing KeyGen Biotech Co., Ltd.)

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Mitochondrial function was also assessed by flow cytometry in the same study