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Conjugating TEM8-targeting antibodies with cytotoxic monomethyl auristatin E was successful in specifically directing the drug to the tumor microenvironment of orthotopic tumors and patient derived xenografts, significantly inducing regression or eradication of tumor growth in pre-clinical models [323]

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Roosevelt Teaching Hospital, Slovakia Updates Copyright 2024 Hong, Huang, Jiang, Ma, Qiu, Luo, Cao, Xu, Chen, Chen, Sun, Fu, Liu, Li, Chen and Qiu

Results revealed that PS-MPs induced depression-like behaviors in zebrafish, characterized by reduced exploration, decreased locomotor activity, and altered social interaction

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