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Neequaye M, Stavnstrup S, Harwood W, Lawrenson T, Hundleby P, Irwin J, et al

A retrospective real-world study conducted in the US that recruited almost 52,000 type 2 diabetes patients treated with two oral antidiabetic agents found that individuals initiating a third oral agent were more persistent than those initiating insulin after a 2-year period [21]

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SGLT2 Inhibitors No pharmacokinetic interaction studies have identified clinically meaningful changes when empagliflozin, dapagliflozin, or canagliflozin are combined with GLP-1 RAs

HGH influences insulin sensitivity and lipid metabolism, whilst retatrutide modulates appetite hormones and incretin signalling

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