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Dermal exposure remains critical for genotoxic or cytotoxic agents like paclitaxel, colchicine, and gemcitabine, which can produce adverse effects through skin absorption even at minimal contact levels [64, 132]

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MSM induced an increase in GSH levels, and again the MSM effect was potentiated by Vit C, reaching values comparable to those observed before exercise

Curcumin, at doses that achieve a hormetic effect (e.g., 10 mg/L or approximately 28 M in vitro ), can enhance antioxidant defense by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, upregulating glutathione (GSH) metabolism, and inducing glutathione S-transferase (GST) activity, particularly isoforms involved in detoxifying lipid peroxidation products such as 4-hydroxynonenal (4-HNE)

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However, please avoid long baths, saunas, intense exercise, and excessive alcohol consumption