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One confounding factor is the complexity of antioxidants, referred to by Halliwell [6] as the antioxidant paradox, or the situation in which antioxidants such as glutathione can possess prooxidant activity causing a hormetic effect enabling the body to bolster its endogenous antioxidant defenses
In contrast, a weak immune system cannot defend itself from harmful invaders, which can cause chronic inflammation, often the root cause of autoimmune disease
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When people with diabetes were given the glutathione precursors cysteine and glycine, their levels of glutathione went up, and their oxidative stress went down, suggesting that GSH supplementation may be very beneficial in preventing type 2 diabetes-related oxidative stress and tissue damage