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It is synthesized in the body from the amino acids lysine and methionine, predominantly in the liver and kidneys

Part of the antioxidant capacity of serum is due to the presence of GSH and the reduced capacity could be associated with a general reduction in GSH due to its conjugation with NAPQI

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NO-system & vasomotor tone: Concentration- and NO-dependent modulation of aortic vasomotion in ex vivo studies (Hsieh 2020)