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Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes
Focus on multi-target R&D: Develop GLP-1/GIP/GCG dual/triple-target agonists to build unrivaled efficacy advantages, with weight loss efficacy reaching up to 25%-35%
Metabolic adaptation and GLP1R desensitization occur in a subset of users, usually after 3-6 months of consistent use
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Teixeira, Fernanda M.G
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