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The bowel and beyond: the enteric nervous system in neurological disorders

This gives us a clear target that would eliminate two birds with one stone, eliminating senescent cells and keeping neighboring cells healthy for longer. Unrelated to the Salk study, scientists have already developed drugs to target acid ceramidase for the treatment of other diseases in which this enzyme also plays a role

[PubMed: 8319375] 115

This small molecule, known as TMAO, has received attention in recent years, with various lines of evidence suggesting a correlation between a higher risk of CVDs and all-cause mortality [39, 40]

doi: 10.1152/ajpcell.00003.2006

10.1530/eje.1.02226 Jolliffe CJ, Janssen I: Distribution of lipoproteins by age and gender in adolescents