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Look for how these reasons may intersect

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In contrast, the elastase treatment reduced the S0 protein signal and increased the signal corresponding to the S2 subunit

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PLoS ONE 3:e1944 Srinivasan R, Ratiney H, Hammond-Rosenbluth KE, Pelletier D, Nelson SJ (2010) MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

Junction nevi may change into compound nevi after childhood, but they remain as junction nevi on palms, soles, and genitalia