They start much earlier, at the formulation stage
Rapid weight loss may occasionally be associated with nutritional deficiencies
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GLP-1 receptor agonists (GLP-1RAs) has the similar physiological function of GLP-1
Proposed mechanisms include enhanced insulinotropic activity, improved adipose tissue handling of nutrients, central effects on appetite and reward pathways, and improved tolerability or pharmacodynamic balance when combined with GLP-1 receptor agonism
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