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The math is straightforward, but mistakes here cascade through every subsequent dose

These drugs mimic the action of a naturally occurring hormone called glucagon like peptide 1

Delayed gastric emptying caused by tirzepatide may theoretically exacerbate gastro-oesophageal reflux, potentially leading to cough

But amidst that clamour there is a significant risk of some producers taking advantage of the proliferation to sell unauthorised versions of the drugs, or using improper marketing practices to gain an unfair and potentially unsafe for patients advantage

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20 There is limited evidence from trials and realworld studies on strategies for managing GI side effects of GLP1RA treatment