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This metabolic dysregulation is defined by systemically reduced levels of metabolites such as amino acids and fatty acids, leading to reduced TCA cycle activity and oxidative phosphorylation, which may ultimately be a major contributor to neuropsychiatric symptoms associated with reduced energy, such as fatigue and other cognitive impairments [43, 62]

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7.1.2.2 Machine learning risk prediction Machine learning algorithms trained on comprehensive epidemiological datasets may accurately predict reproductive health outcomes based on individual cumulative EED exposure profiles (138)

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