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Similarly, KD pre-treatment for 1 month resulted in an increase in gut pathogenic bacteria and a decrease in beneficial bacteria in inflammatory bowel disease mice, which increased gut and systemic inflammation, disrupted the gut barrier, and exacerbated colitis (230)

Therefore, agents that target glutamine utilization may, when used in combination with an anti-PD-L1 antibody, boost antitumor immunity 58

[DOI] [PMC free article] [PubMed] [Google Scholar] 192.Schremmer B., Manevich Y., Feinstein S.I., Fisher A.B

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Glutathione Recycler K57 is recommended to support glutathione synthesis and recycling