ZIP4 increases expression of transcription factor ZEB1 to promote Integrin 31 signaling and inhibit expression of the gemcitabine transporter ENT1 in pancreatic cancer cells
Our data support a dual-axis model in which a pharmacologic trigger interacts with modulation of the immune-tolerance threshold, suggesting that ICI exposure may lower immune tolerance and thereby amplify subsequent drug-induced, T cellmediated immune responses
In those cases, preservative-free sterile water for injection (without benzyl alcohol) is required
Nikpoor B, Turecki G, Fournier C, Theroux P, Rouleau GA
Pei L, Che R, He L
Kerins MJ, Milligan J, Wohlschlegel JA, Ooi A