211 HFD-induced fatty liver may promote liver metastasis by facilitating the secretion of hepatocyte-derived extracellular vesicles (EVs), which transfer Yes-associated protein (YAP) signaling-regulating microRNAs, hence elevating nuclear YAP expression, CYR61 expression, and M2-like macrophage infiltration
Transcriptomic analysis of High ADA expressing cells shows increased expression of P2 receptors, Inflammatory cytokines and osteoclast markers We further validated the in vitro experiments on RAW 264.7 cells, showing elevated cytokine expression in the presence of ADA is of consequence in vivo
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Mol Neurobiol 53:34623476 Shaughnessy LM, Swanson JA (2007) The role of the activated macrophage in clearing Listeria monocytogenes infection
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