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The mechanism is unclear but may relate to rapid B12 mobilization in deficient patients

It has been extensively studied in animal models for its regenerative effects across multiple tissue types, including tendon, ligament, vascular endothelium, muscle, and intestinal mucosa

Was there randomisation, blinding and a control group

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Splitting a 12mg weekly dose into two 6mg injections (for example Monday and Thursday) reduces peak plasma concentration and can significantly reduce gastrointestinal side effects

At 15mg, this is a legitimate medical conversation